Secondary Hypertension

Secondary Hypertension

0.0 7.70MB 0 ¤68.00
Version 1.0 Updated 2026-04-08 Developer ATIF ELNIL

Description

Secondary Hypertension is a comprehensive clinical reference tool for healthcare professionals investigating and managing secondary causes of hypertension

Secondary Hypertension is a comprehensive clinical reference tool for healthcare professionals investigating and managing secondary causes of hypertension. Designed by a neurologist at St George's London, this app covers the full investigation pathway from when to suspect a secondary cause through to targeted management.
 
Secondary hypertension accounts for 5-10% of all hypertension cases and up to 20% of resistant hypertension. Early identification of a treatable secondary cause can lead to cure or marked improvement in blood pressure control.
 
CLINICAL CONTENT:
 
• When to Suspect Secondary Hypertension — Clear criteria including onset under 40, resistant hypertension, spontaneous hypokalaemia, episodic symptoms, and abdominal bruit
 
• Renal Parenchymal Disease — CKD, glomerulonephritis, polycystic kidney disease, reflux nephropathy, diabetic nephropathy. BP targets (NICE NG203/KDIGO 2021) and drug treatment including ACEi/ARB first-line guidance
 
• Renovascular Hypertension — Atherosclerotic renal artery stenosis with clinical clues, ASTRAL and CORAL trial evidence. Fibromuscular dysplasia including string of beads sign, PTA without stenting, and MRA head for aneurysm screening
 
• Primary Hyperaldosteronism — Screening indications, aldosterone:renin ratio methodology, drug washout requirements, confirmatory tests (IV saline infusion, fludrocortisone suppression), adrenal vein sampling, and treatment by subtype (spironolactone vs laparoscopic adrenalectomy)
 
• Phaeochromocytoma — Classic triad, rule of 10s, hereditary syndromes (MEN2, VHL, NF1, SDHx), plasma free metanephrines vs 24h urinary, CT HU threshold, and critical pre-operative alpha-blockade protocol. NEVER beta-blocker before alpha-blockade.
 
• Cushing Syndrome — Clinical features, overnight dexamethasone suppression test, 24h urinary free cortisol, late-night salivary cortisol, ACTH-dependent vs independent differentiation, inferior petrosal sinus sampling
 
• Thyroid and Other Endocrine — Hypothyroid (diastolic hypertension) vs hyperthyroid (systolic, wide pulse pressure), acromegaly (IGF-1 screening, OGTT with GH), primary hyperparathyroidism (bones, stones, groans, moans), parathyroidectomy
 
• Obstructive Sleep Apnoea — Mechanism of hypertension, STOP-BANG screening, nocturnal non-dipping pattern, polysomnography, CPAP BP reduction evidence, spironolactone for pharyngeal oedema
 
• Drug-induced Hypertension — 11-drug table including NSAIDs, combined OCP (RAAS activation), ciclosporin (CCB first-line), VEGF inhibitors (severe hypertension), cocaine (avoid beta-blockers), liquorice (11-beta-HSD2 inhibition), and herbal supplements
 
• Investigations — When to investigate checklist, targeted blood tests by suspected cause, imaging algorithm table (first-line vs gold standard for each cause)
 
FEATURES:
• Adjustable font size (A-/A+) for bedside use
• Tab-based navigation within each section
• All references tappable — links to PubMed, NICE, and ESC guidelines
• Works fully offline — no internet connection required
• No advertisements
 
Based on ESC/ESH 2023, NICE NG136, Funder 2016, Lenders 2014, Nieman 2015, Rimoldi 2014, ASTRAL 2009, CORAL 2014, NICE NG203.
 
FOR QUALIFIED HEALTHCARE PROFESSIONALS ONLY. This app is intended as a clinical reference tool for use by doctors, nurses, and allied health professionals. It is not intended for use by patients or the general public. It does not replace clinical judgement or local protocols. Not a regulated medical device — exempt under MHRA Software Guidance 2020, EU MDR Article 2(1), and FDA 21st Century Cures Act Section 3060.
 
© 2026 Dr Atif Elnil. All rights reserved. Last reviewed 2026.
Category: () Version: 1.0 BundleId: com.atifelnil.Secondary-Hypertension Developer: ATIF ELNIL Updated: 2026-04-08

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